Detail Information

P450 Protein:

P450 SymbolCYP134A1
Protein NamePulcherriminic acid synthase
Uniprot IDO34926
EC Number1.14.15.13
Gene ID 936624
SpeciesBacillus subtilis (strain 168)
Txid 224308
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C12H22N2O2 → C12H22N2O3
Reaction TypeOxidation
Chemical BondNH

Cyclo(L-Leucyl-L-Leucyl)

CYP134A1

(3S,6S)-1-hydroxy-3,6-bis(2-methylpropyl)piperazine-2,5-dione

Substrate Information:

Substrate Name Cyclo(L-Leucyl-L-Leucyl)
Substrate Chemical FormulaC12H22N2O2
Substrate PubChem CID192731
Substrate SmilesCC(C)C[C@H]1C(=O)N[C@H](C(=O)N1)CC(C)C
Substrate Structure

Product Information:

Product Name (3S,6S)-1-hydroxy-3,6-bis(2-methylpropyl)piperazine-2,5-dione
Product Chemical FormulaC12H22N2O3
Product SmilesCC(C[C@@H]1NC(=O)[C@H](CC(C)C)N(O)C1=O)C
Product Structure

References:

Title: Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase.
PMID: 20690619
Journal: Biochemistry
Year: 2010/6/27

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics