Detail Information
P450 Protein:
| P450 Symbol | CYP706B1 |
| Protein Name | p450 monooxygenase |
| Uniprot ID | Q947C2 |
| Species | Gossypium arboreum (Tree cotton) (Gossypium nanking) |
| Txid | 29729 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C15H24 → C15H24O |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
| Solvents | Water |
| Conditions | 20 min, pH 7.4, 30°C |
| Transformations | Hydroxylation at an Aliphatic Carbon |
CYP706B1
Substrate Information:
| Substrate Name | alpha-Cadinene |
| Substrate Chemical Formula | C15H24 |
| Substrate PubChem CID | 441005 |
| Substrate Smiles | [C@@H](C)(C)[C@H]1[C@]2(C(=C(C)CC1)CCC(C)=C2)[H] |
| Substrate Structure |
Product Information:
| Product Name | (4aR,5S)-1,2,4a,5,6,7-Hexahydro-3,8-dimethyl-5-(1-methylethyl)-1-naphthalenol |
| Product Chemical Formula | C15H24O |
| Product PubChem CID | 15983950 |
| Product CAS Number | 625412-95-5 |
| Product Smiles | C(C)(C)[C@H]1[C@]2(C(C(O)CC(C)=C2)=C(C)CC1)[H] |
| Product Structure |
References:
| Title: | Inhibitor and substrate activities of sesquiterpene olefins toward +-δ-cadinene-8-hydroxylase, a cytochrome P450 monooxygenase (CYP706B1). |
| PMID: | 20801466 |
| Journal: | Phytochemistry (Elsevier) |
| Year: | 2010/11/1 |