Detail Information
P450 Protein:
| P450 Symbol | |
| Protein Name | Cytochrome P450 monooxygenase |
| Uniprot ID | C7SFP5 |
| Species | Rhodococcus sp. ECU0066 |
| Txid | 470743 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C7H7ClS → C7H7ClO2S |
| Reaction Type | Oxidation |
| Chemical Bond | S |
| Solvents | Water |
| Conditions | 24 h, pH 7, 30°C |
| Transformations | Oxidation of Thioethers to Sulfoxides and Sulfones |
Substrate Information:
| Substrate Name | 1-Chloro-4-(methylthio)benzene |
| Substrate Chemical Formula | C7H7ClS |
| Substrate PubChem CID | 31243 |
| Substrate Smiles | CSC1=CC=C(C=C1)Cl |
| Substrate Structure |
Product Information:
| Product Name | Methyl 4-chlorophenyl sulfone |
| Product Chemical Formula | C7H7ClO2S |
| Product PubChem CID | 7395 |
| Product CAS Number | 98-57-7 |
| Product Smiles | CS(=O)(=O)C1=CC=C(C=C1)Cl |
| Product Structure |
References:
| Title: | Sequence analysis and heterologous expression of a new cytochrome P450 monooxygenase from Rhodococcus sp. for asymmetric sulfoxidation. |
| PMID: | 19633839 |
| Journal: | Applied Microbiology and Biotechnology |
| Year: | 2009/7/25 |