Detail Information

P450 Protein:

P450 SymbolCYP2C9
Protein NameCytochrome P450 2C9
Uniprot IDP11712
EC Number1.14.14.1; 1.14.14.51; 1.14.14.52; 1.14.14.53
Gene ID 1559
SpeciesHomo sapiens
Txid 9606
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C21H18N2O3 → C20H16N2O3
Reaction TypeOxidation
Chemical BondC-O

4-[(7-methoxy-1-methylpyrido[3,4-b]indol-9-yl)methyl]benzoic acid

CYP2C9

4-[(1-methyl-7-oxo-2H-pyrido[3,4-b]indol-9-yl)methyl]benzoic acid

Substrate Information:

Substrate Name 4-[(7-methoxy-1-methylpyrido[3,4-b]indol-9-yl)methyl]benzoic acid
Substrate Chemical FormulaC21H18N2O3
Substrate PubChem CID44815873
Substrate SmilesC(O)(=O)C1C=CC(CN2C3C=C(C=CC=3C3C=CN=C(C2=3)C)OC)=CC=1
Substrate Structure

Product Information:

Product Name 4-[(1-methyl-7-oxo-2H-pyrido[3,4-b]indol-9-yl)methyl]benzoic acid
Product Chemical FormulaC20H16N2O3
Product PubChem CID44815874
Product SmilesC(O)(=O)C1C=CC(CN2C3C=C(C=CC=3C3C=CN=C(C2=3)C)O)=CC=1
Product Structure

References:

Title: Beta-Carbolin-Derivates as Substrates for an Enzyme
Patent ID: WO2010015636
Journal:
Year: 2010/2/11

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics