Detail Information

P450 Protein:

P450 SymbolCYP2D6
Protein NameCytochrome P450 2D6
Uniprot IDP10635
EC Number1.14.14.1
Gene ID 1565
SpeciesHomo sapiens
Txid 9606
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C14H17N2O+ → C13H15N2O+
Reaction TypeOxidation
Chemical BondC-O

7-methoxy-1,2-dimethyl-4,9-dihydro-3H-pyrido[3,4-b]indol-2-ium

CYP2D6

1,2-dimethyl-4,9-dihydro-3H-pyrido[3,4-b]indol-2-ium-7-ol

Substrate Information:

Substrate Name 7-methoxy-1,2-dimethyl-4,9-dihydro-3H-pyrido[3,4-b]indol-2-ium
Substrate Chemical FormulaC14H17N2O+
Substrate PubChem CID51062664
Substrate SmilesCC1=[N+](CCC2=C1NC3=C2C=CC(=C3)OC)C
Substrate Structure

Product Information:

Product Name 1,2-dimethyl-4,9-dihydro-3H-pyrido[3,4-b]indol-2-ium-7-ol
Product Chemical FormulaC13H15N2O+
Product PubChem CID70919924
Product SmilesCC1=[N+](CCC2=C1NC3=C2C=CC(=C3)O)C
Product Structure

References:

Title: Beta-Carbolin-Derivates as Substrates for an Enzyme
Patent ID: WO2010015636
Journal:
Year: 2010/2/11

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics