Detail Information
P450 Protein:
| P450 Symbol | CYP71AV8 |
| Protein Name | Cytochrome P450 71AV8 |
| Uniprot ID | E1B2Z9 |
| EC Number | 1.14.13.- |
| Species | Cichorium intybus |
| Txid | 13427 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | membrane |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C15H24 → C15H22O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Solvents | Water |
| Transformations | 1.Hydroxylation at an Aromatic Carbon |
CYP71AV8
Substrate Information:
| Substrate Name | amorphadiene |
| Substrate Chemical Formula | C15H24 |
| Substrate PubChem CID | 11052747 |
| Substrate Smiles | C[C@@H]1CC[C@H]([C@@H]2[C@H]1CCC(=C2)C)C(=C)C |
| Substrate Structure |
Product Information:
| Product Name | Artemisinic acid |
| Product Chemical Formula | C15H22O2 |
| Product PubChem CID | 10922465 |
| Product CAS Number | 80286-58-4 |
| Product Smiles | C[C@@H]1CC[C@H]([C@@H]2[C@H]1CCC(=C2)C)C(=C)C(=O)O |
| Product Structure |
References:
| Title: | A chicory cytochrome P450 mono-oxygenase CYP71AV8 for the oxidation of (+)-valencene. |
| PMID: | 21115006 |
| Journal: | FEBS Letters |
| Year: | 2011/1/3 |