Detail Information
P450 Protein:
| P450 Symbol | CYP199A4 |
| Protein Name | Cytochrome P450 199A4 |
| Uniprot ID | Q2IU02 |
| EC Number | 1.14.99.15 |
| Species | Rhodopseudomonas palustris HaA2 |
| Txid | 316058 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C8H14O2 → C8H14O3 |
| Reaction Type | Oxidation |
| Chemical Bond | CH3 |
CYP199A4
Substrate Information:
| Substrate Name | trans-4-Methylcyclohexane-1-carboxylic acid |
| Substrate Chemical Formula | C8H14O2 |
| Substrate Smiles | C(O)(=O)[C@H]1CC[C@H](C)CC1 |
| Substrate Structure |
Product Information:
| Product Name | trans-4-(Hydroxymethyl)cyclohexanecarboxylic acid (ACI) |
| Product Chemical Formula | C8H14O3 |
| Product CAS Number | 66185-74-8 |
| Product Smiles | C(O)(=O)[C@H]1CC[C@H](CO)CC1 |
| Product Structure |
References:
| Title: | Investigation of the substrate range of CYP199A4: modification of the partition between hydroxylation and desaturation activities by substrate and protein engineering. |
| PMID: | 23135838 |
| Journal: | Chemistry - A European Journal |
| Year: | 2012/11/7 |