Detail Information
P450 Protein:
| P450 Symbol | CYP90D2 |
| Protein Name | Cytochrome P450 90D2 |
| Uniprot ID | Q94IW5 |
| EC Number | 1.14.19.- |
| Species | Oryza sativa subsp. japonica (Rice) |
| Txid | 39947 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C28H48O2 + C21H25N7O17P3-3 → C28H48O3 + C21H26N7O17P3-4 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Solvents | Water |
| Conditions | 6 h, pH 7.25, 30°C |
| Transformations | Hydroxylation at an Aliphatic Carbon |
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CYP90D2
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Substrate Information:
| Substrate Name | (22S,24R)-22-Hydroxy-5alpha-ergostan-3-one |
| Substrate Chemical Formula | C28H48O2 |
| Substrate PubChem CID | 46878488 |
| Substrate Smiles | C[C@H](C[C@@H]([C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CCC(=O)C4)C)C)O)C(C)C |
| Substrate Structure |
| Substrate Name | NADP+ |
| Substrate Chemical Formula | C21H25N7O17P3-3 |
| Substrate PubChem CID | 162422398 |
| Substrate Smiles | C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)OP(=O)([O-])[O-])O)O)C(=O)N |
| Substrate Structure |
Product Information:
| Product Name | 3-Dehydro-6-deoxoteasterone |
| Product Chemical Formula | C28H48O3 |
| Product PubChem CID | 16061345 |
| Product CAS Number | 164034-48-4 |
| Product Smiles | C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CCC(=O)C4)C)C)[C@H]([C@@H]([C@@H](C)C(C)C)O)O |
| Product Structure |
| Product Name | NADPH(4-) |
| Product Chemical Formula | C21H26N7O17P3-4 |
| Product PubChem CID | 15983949 |
| Product Smiles | C1C=CN(C=C1C(=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)OP(=O)([O-])[O-])O)O)O |
| Product Structure |
References:
| Title: | Rice CYP90D2 and CYP90D3 catalyze C-23 hydroxylation of brassinosteroids in vitro. |
| PMID: | 22846333 |
| Journal: | Plant Physiology and Biochemistry (Issy-les-Moulineaux, France) |
| Year: | 2012/9/ |