Detail Information
P450 Protein:
| P450 Symbol | CYP199A2 |
| Protein Name | Cytochrome p450 CYP199A2 |
| Uniprot ID | Q6N8N2 |
| EC Number | 1.14.99.15 |
| Gene ID | 66892909 |
| Species | Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) |
| Txid | 258594 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C9H8O3 → C9H8O4 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Solvents | Water |
| Conditions | 40 min, pH 7.5, 30°C |
| Transformations | 1.Hydroxylation of Aromatic Compounds 2.Hydroxylation at an Aromatic Carbon |
CYP199A2
Substrate Information:
| Substrate Name | trans-4-Hydroxycinnamic acid |
| Substrate Chemical Formula | C9H8O3 |
| Substrate PubChem CID | 637542 |
| Substrate Smiles | C(=C/C(O)=O)C1=CC=C(O)C=C1 |
| Substrate Structure |
Product Information:
| Product Name | trans-Caffeic acid |
| Product Chemical Formula | C9H8O4 |
| Product PubChem CID | 689043 |
| Product CAS Number | 501-16-6 |
| Product Smiles | C(=C/C(O)=O)C1=CC(O)=C(O)C=C1 |
| Product Structure |
References:
| Title: | Biotechnological production of caffeic acid by bacterial cytochrome P450 CYP199A2. |
| PMID: | 22729547 |
| Journal: | Applied and Environmental Microbiology |
| Year: | 2012/8/9 |