Detail Information

P450 Protein:

P450 SymbolP450RhF
Protein NameCytochrome P450 RhF
Uniprot IDQ8KU27
SpeciesRhodococcus sp. NCIMB 9784
Txid 157732
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C10H12O3 → C10H12O4
Reaction TypeOxidation
Chemical BondCH
SolventsDimethyl sulfoxide,Water
Conditions48 h, pH 7.8, 20°C
Transformations1.Formation of Alkyl Halides/ Alcohols from Ethers /Silyl Ethers 2.Hydroxylation of Aromatic Compounds 3.Hydroxylation at an Aromatic Carbon

1-(4-Ethoxy-2-hydroxyphenyl)ethanone

P450RhF

1-(4-Ethoxy-2,5-dihydroxyphenyl)ethanone

Substrate Information:

Substrate Name 1-(4-Ethoxy-2-hydroxyphenyl)ethanone
Substrate Chemical FormulaC10H12O3
Substrate PubChem CID2775163
Substrate SmilesO=C(C1=CC=C(OCC)C=C1O)C
Substrate Structure

Product Information:

Product Name 1-(4-Ethoxy-2,5-dihydroxyphenyl)ethanone
Product Chemical FormulaC10H12O4
Product CAS Number58084-93-8
Product SmilesO=C(C=1C=C(O)C(OCC)=CC1O)C
Product Structure

References:

Title: Substrate promiscuity of cytochrome P450 RhF
DOI: https://doi.org/10.1039/C3CY00091E
Journal: Catalysis Science & Technology
Year: 2013/4/3

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics