Detail Information
P450 Protein:
| P450 Symbol | CYP199A4 |
| Protein Name | Cytochrome P450 199A4 |
| Uniprot ID | Q2IU02 |
| EC Number | 1.14.99.15 |
| Species | Rhodopseudomonas palustris HaA2 |
| Txid | 316058 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C8H8O4 → C7H6O4 |
| Reaction Type | Reduction |
| Chemical Bond | C-O |
| Transformations | Formation of Alkyl Halides/ Alcohols from Ethers /Silyl Ethers |
CYP199A4
Substrate Information:
| Substrate Name | 4-Methoxysalicylic acid |
| Substrate Chemical Formula | C8H8O4 |
| Substrate PubChem CID | 75231 |
| Substrate Smiles | O=C(O)C1=CC=C(OC)C=C1O |
| Substrate Structure |
Product Information:
| Product Name | 2,4-Dihydroxybenzoic acid |
| Product Chemical Formula | C7H6O4 |
| Product PubChem CID | 1491 |
| Product CAS Number | 89-86-1 |
| Product Smiles | O=C(O)C1=CC=C(O)C=C1O |
| Product Structure |
References:
| Title: | CYP199A4 catalyses the efficient demethylation and demethenylation of para-substituted benzoic acid derivatives |
| DOI: | https://doi.org/10.1039/C5RA08730A |
| Journal: | RSC Advances |
| Year: | 2015/6/2 |