Detail Information
P450 Protein:
| P450 Symbol | |
| Protein Name | Cytochrome P450 |
| Uniprot ID | A0A218N7J9 |
| Species | Colletotrichum lini |
| Txid | 500171 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C19H28O2 → C19H28O4 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Conditions | 72 h, 28°C |
| Transformations | Hydroxylation at an Aliphatic Carbon |
Substrate Information:
| Substrate Name | Dehydroepiandrosterone |
| Substrate Chemical Formula | C19H28O2 |
| Substrate PubChem CID | 5881 |
| Substrate Smiles | C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC=C4[C@@]3(CC[C@@H](C4)O)C |
| Substrate Structure |
Product Information:
| Product Name | 3beta,7alpha,15alpha-Trihydroxyandrost-5-en-17-one |
| Product Chemical Formula | C19H28O4 |
| Product PubChem CID | 45092605 |
| Product CAS Number | 2963-69-1 |
| Product Smiles | C[C@]12CC[C@@H](CC1=C[C@H]([C@@H]3[C@@H]2CC[C@]4([C@H]3[C@H](CC4=O)O)C)O)O |
| Product Structure |
References:
| Title: | Improvement of NADPH-dependent P450-mediated biotransformation of 7α,15α-diOH-DHEA from DHEA by a dual cosubstrate-coupled system. |
| PMID: | 26032779 |
| Journal: | Steroids |
| Year: | 2015/9/ |