Detail Information
P450 Protein:
| P450 Symbol | bezC |
| Protein Name | Cytochrome P450 monooxygenase |
| Uniprot ID | A0A2Z5X6T5 |
| Species | Streptomyces sp. RI18 |
| Txid | 1894972 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C10H20O7P2 → C11H22O8P2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH3 |
| Solvents | Water |
| Conditions | 1 h, pH 7.4, 30°C |
bezC
Substrate Information:
| Substrate Name | [(2E)-3,7-dimethylocta-2,6-dienyl] phosphono hydrogen phosphate |
| Substrate Chemical Formula | C10H20O7P2 |
| Substrate PubChem CID | 445995 |
| Substrate Smiles | CC(=CCC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)C |
| Substrate Structure |
Product Information:
| Product Name | Diphosphoric acid, P-[(2Z)-3-(hydroxymethyl)-6,7-dimethyl-2,6-octadien-1-yl] ester |
| Product Chemical Formula | C11H22O8P2 |
| Product CAS Number | 2232204-20-3 |
| Product Smiles | C(CCC(=C(C)C)C)(=C/COP(OP(=O)(O)O)(=O)O)/CO |
| Product Structure |
References:
| Title: | Unprecedented Cyclization Catalyzed by a Cytochrome P450 in Benzastatin Biosynthesis. |
| PMID: | 29716187 |
| Journal: | Journal of the American Chemical Society |
| Year: | 2018/5/2 |