Detail Information
P450 Protein:
| P450 Symbol | CYP102A1 |
| Protein Name | Bifunctional cytochrome P450/NADPH--P450 reductase |
| Uniprot ID | P14779 |
| EC Number | 1.14.14.1; 1.6.2.4 |
| Gene ID | 93643681 |
| Species | Bacillus megaterium (strain ATCC 14581 / DSM 32 / JCM 2506 / NBRC 15308 / NCIMB 9376 / NCTC 10342 / NRRL B-14308 / VKM B-512) |
| Txid | 1348623 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C15H14O5 → C15H14O6 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Solvents | Dimethyl sulfoxide;Water |
| Conditions | 60 min, 37°C |
| Transformations | 1.Hydroxylation at an Aromatic Carbon 2.Hydroxylation of Aromatic Compounds |
CYP102A1
Substrate Information:
| Substrate Name | 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one |
| Substrate Chemical Formula | C15H14O5 |
| Substrate PubChem CID | 4788 |
| Substrate Smiles | C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O |
| Substrate Structure |
Product Information:
| Product Name | 3-(3,4-dihydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one |
| Product Chemical Formula | C15H14O6 |
| Product PubChem CID | 11778945 |
| Product CAS Number | 57765-66-9 |
| Product Smiles | C1=CC(=C(C=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O)O |
| Product Structure |
References:
| Title: | Composition for Producing 3-Hydroxy Phloretin |
| Patent ID: | WO2019066446 |
| Journal: | |
| Year: | 2019/4/4 |