Detail Information
P450 Protein:
| P450 Symbol | CYP52A12 |
| Protein Name | CYP52A12 |
| Uniprot ID | Q874J5 |
| Species | Candida tropicalis (Yeast) |
| Txid | 5482 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C12H26 → C10H18O4 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Solvents | Water |
| Conditions | 129 h, pH 7.5, 30°C |
CYP52A12
Substrate Information:
| Substrate Name | dodecane |
| Substrate Chemical Formula | C12H26 |
| Substrate PubChem CID | 8182 |
| Substrate Smiles | CCCCCCCCCCCC |
| Substrate Structure |
Product Information:
| Product Name | decanedioic acid |
| Product Chemical Formula | C10H18O4 |
| Product PubChem CID | 5192 |
| Product CAS Number | 111-20-6 |
| Product Smiles | C(CCCCC(=O)O)CCCC(=O)O |
| Product Structure |
References:
| Title: | Directed Evolution of CYP52A12 Gene and Its Use in Dicarboxylic Acid Production |
| Patent ID: | EP3550014 |
| Journal: | |
| Year: | 2019/10/9 |