Detail Information

P450 Protein:

P450 SymbolRebP
Protein NameRebP-like cytochrome P450
Uniprot IDA0A8F5FCX1
SpeciesStreptomyces sp.
Txid 1931
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C22H15N3O4 → C20H13N3O
Reaction Typecyclization reaction
Chemical Bond
Conditions20 h, pH 7.0, 25°C; 15 min, 85°C

3,4-bis(1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylic acid

RebP

3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4,6,8,10,15,17,19,21-nonaen-12-one

Substrate Information:

Substrate Name 3,4-bis(1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylic acid
Substrate Chemical FormulaC22H15N3O4
Substrate PubChem CID11326613
Substrate SmilesC1=CC=C2C(=C1)C(=CN2)C3=C(NC(=C3C4=CNC5=CC=CC=C54)C(=O)O)C(=O)O
Substrate Structure

Product Information:

Product Name 3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4,6,8,10,15,17,19,21-nonaen-12-one
Product Chemical FormulaC20H13N3O
Product PubChem CID3815
Product CAS Number85753-43-1
Product SmilesC1C2=C3C4=CC=CC=C4NC3=C5C(=C2C(=O)N1)C6=CC=CC=C6N5
Product Structure

References:

Title: 一种星孢菌素中间体K252c及其衍生物的催化合成体系及催化合成方法
Patent ID: CN112852899
Journal:
Year: 2021/5/28

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics