P450 Protein:

P450 Symbol	RebP
Protein Name	RebP-like cytochrome P450
Uniprot ID	A0A8F5FCX1
Species	Streptomyces sp.
Txid	1931
P450 Protein Structure	Go to AlphaFold Website Model Confidence (pLDDT) Very high (>90) High (90 > 70) Low (70 > 50) Very low (<50) Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence	GO

Reaction Scheme:

Chemical Conversion	C11H12N2O2 → C22H15N3O4
Reaction Type	cyclization reaction
Chemical Bond
Solvents	Water
Conditions	20 h, pH 7.0, 25°C; 15 min, 85°C
Transformations	1.Transamination 2.Decarboxylation of Aliphatic Acids 3.Reduction of the C-N Bond/ Deamination

Substrate Information:

Substrate Name	(2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
Substrate Chemical Formula	C11H12N2O2
Substrate PubChem CID	6305
Substrate Smiles	C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)O)N
Substrate Structure	Download SDF

Product Information:

Product Name	3,4-bis(1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylic acid
Product Chemical Formula	C22H15N3O4
Product PubChem CID	11326613
Product CAS Number	150044-68-1
Product Smiles	C1=CC=C2C(=C1)C(=CN2)C3=C(NC(=C3C4=CNC5=CC=CC=C54)C(=O)O)C(=O)O
Product Structure	Download SDF

References: