P450 Protein:

P450 Symbol
Protein Name	L48F-S49A-I61F-L120T-K352I-L356P-W119I-L125D Mutant protein
Uniprot ID
Species	Siraitia grosvenorii (Monk's fruit) (Luo han guo)
Txid	190515
P450 Protein Structure	Go to AlphaFold Website Model Confidence (pLDDT) Very high (>90) High (90 > 70) Low (70 > 50) Very low (<50) Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence	GO

Reaction Scheme:

Chemical Conversion	C60H102O29 → C30H50O2
Reaction Type	Hydrolysis
Chemical Bond
Conditions	48 h, rt
Transformations	Hydrolysis of Acetals/ Orthoesters/ Enol Ethers and Similar Compounds

Substrate Information:

Substrate Name	Mogroside V
Substrate Chemical Formula	C60H102O29
Substrate PubChem CID	24721270
Substrate Smiles	C[C@H](CC[C@H](C(C)(C)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)[C@H]4CC[C@@]5([C@@]4(C[C@H]([C@@]6([C@H]5CC=C7[C@H]6CC[C@@H](C7(C)C)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)O)O)O)C)O)C)C
Substrate Structure	Download SDF

Product Information:

Product Name	19-Norlanosta-5,24-diene-3,11-diol, 9-methyl-, (3beta,9beta,10alpha,11beta)-
Product Chemical Formula	C30H50O2
Product CAS Number	87593-10-0
Product Smiles	C[C@]12[C@]3([C@](C)([C@]4(C(=CC3)C(C)(C)[C@@H](O)CC4)[H])[C@@H](O)C[C@]1(C)[C@@]([C@@H](CCC=C(C)C)C)(CC2)[H])[H]
Product Structure	Download SDF

References: