Detail Information
P450 Protein:
| P450 Symbol | CYP102A1 |
| Protein Name | P450 BM3 mutants A2 (Asp251Gly/Gln307His) |
| Uniprot ID | |
| Species | Bacillus megaterium (strain ATCC 14581 / DSM 32 / JCM 2506 / NBRC 15308 / NCIMB 9376 / NCTC 10342 / NRRL B-14308 / VKM B-512) |
| Txid | 1348623 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C10H18O → C10H18O2 |
| Reaction Type | Oxidation |
| Chemical Bond | C=C |
CYP102A1
Substrate Information:
| Substrate Name | Geraniol |
| Substrate Chemical Formula | C10H18O |
| Substrate Smiles | C(/C)(=C/CC/C(/C)=C/CO)C |
| Substrate Structure |
Product Information:
| Product Name | 6,7-Epoxy-geraniol |
| Product Chemical Formula | C10H18O2 |
| Product Smiles | O1C(CC/C(/C)=C/CO)C1(C)C |
| Product Structure |
References:
| Title: | Enhanced and specific epoxidation activity of P450 BM3 mutants for the production of high value terpene derivatives. |
| PMID: | 36505709 |
| Journal: | RSC Advances |
| Year: | 2022/11/28 |