Detail Information
P450 Protein:
| P450 Symbol | CYP71CD2 |
| Protein Name | Dihydroniloticin synthase CYP71CD2 |
| Uniprot ID | |
| Species | Azadirachta indica |
| Txid | 124943 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C29H48O → C29H48O2 |
| Reaction Type | Oxidation |
| Chemical Bond | C=C |
| Solvents | Water |
CYP71CD2
Substrate Information:
| Substrate Name | Tirucalla-7,24-dien-3-ol |
| Substrate Chemical Formula | C29H48O |
| Substrate Smiles | C1C[C@@](C)2[C@]([H])3CCC4[C@]([H])([C@H](CC/C=C(C)/C)C)CC[C@]4(C)C3=CC[C@@]2([H])C(C)(C)[C@H]1O |
| Substrate Structure |
Product Information:
| Product Name | Dihydroniloticin |
| Product Chemical Formula | C29H48O2 |
| Product Smiles | C1C[C@@](C)2[C@]([H])3CCC4[C@]([H])([C@H](CCC5OC5(C)C)C)CC[C@]4(C)C3=CC[C@@]2([H])C(C)(C)[C@H]1O |
| Product Structure |
References:
| Title: | Metabolic Engineering of Saccharomyces cerevisiae for de Novo Dihydroniloticin Production Using Novel CYP450 from Neem (Azadirachta indica). |
| PMID: | 35258300 |
| Journal: | Journal of Agricultural and Food Chemistry |
| Year: | 2022/3/8 |