Detail Information
P450 Protein:
| P450 Symbol | CYP74 |
| Protein Name | Divinyl ether synthase CYP74 (AsDES) (Colneleate synthase) (EC 4.2.1.121) (Etheroleic acid synthase CYP74) (EC 4.2.1.183) |
| Uniprot ID | Q2WE96 |
| EC Number | 4.2.1.121; 4.2.1.183 |
| Species | Allium sativum (Garlic) |
| Txid | 4682 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C18H29O4- → C18H27O3- + H2O |
| Reaction Type | Elimination |
| Chemical Bond | |
| RheaID | 28178 |
CYP74
+
Substrate Information:
| Substrate Name | (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate |
| Substrate Chemical Formula | C18H29O4- |
| Substrate PubChem CID | 49852426 |
| Substrate Smiles | CCC=CCC=CC=CC(CCCCCCCC(=O)[O-])OO |
| Substrate Structure |
Product Information:
| Product Name | colnelenate |
| Product Chemical Formula | C18H27O3- |
| Product PubChem CID | 25245649 |
| Product Smiles | CCC=CCC=CC=COC=CCCCCCCC(=O)[O-] |
| Product Structure |
| Product Name | H2O |
| Product Chemical Formula | H2O |
| Product PubChem CID | 962 |
| Product CAS Number | 7732-18-5 |
| Product Smiles | O |
| Product Structure |
References:
| Title: | Divinyl ether synthesis in garlic bulbs. |
| PMID: | 18326559 |
| Journal: | European journal of biochemistry |
| Year: | 1995/9/4 |
| Title: | The lipoxygenase pathway in garlic (Allium sativum L.) bulbs: detection of the novel divinyl ether oxylipins. |
| PMID: | 7672118 |
| Journal: | FEBS letters |
| Year: | 2008/1/ |
| Title: | Divinyl ether synthase from garlic (Allium sativum L.) bulbs: sub-cellular localization and substrate regio-and stereospecificity. |
| PMID: | 8690066 |
| Journal: | Journal of experimental botany |
| Year: | 1997/4/1 |
| Title: | On the mechanism of biosynthesis of divinyl ether oxylipins by enzyme from garlic bulbs. |
| PMID: | 9128734 |
| Journal: | |
| Year: | 1996/6/17 |