Detail Information
P450 Protein:
| P450 Symbol | CYP5164B1 |
| Protein Name | Epoxyalcohol synthase CYP5164B1 (EsEAS) (EC 4.2.1.-) (Cytochrome P450 5164B1) |
| Uniprot ID | A0A1L3HS58 |
| EC Number | 4.2.1.- |
| Species | Ectocarpus siliculosus (Brown alga) (Conferva siliculosa) |
| Txid | 2880 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C18H31O4- → C18H31O4- |
| Reaction Type | Cyclization |
| Chemical Bond | C=C |
| RheaID | 75591 |
CYP5164B1
Substrate Information:
| Substrate Name | (9S)-hydroperoxy-(10E,12Z)-octadecadienoate |
| Substrate Chemical Formula | C18H31O4- |
| Substrate PubChem CID | 49852425 |
| Substrate Smiles | CCCCCC=CC=CC(CCCCCCCC(=O)[O-])OO |
| Substrate Structure |
Product Information:
| Product Name | (11S)-hydroxy-(9S,10S)-epoxy-(12Z)-octadecenoate |
| Product Chemical Formula | C18H31O4- |
| Product PubChem CID | 168007588 |
| Product Smiles | CCCCCC=CC(C1C(O1)CCCCCCCC(=O)[O-])O |
| Product Structure |
References:
| Title: | Epoxyalcohol synthase of Ectocarpus siliculosus. First CYP74-related enzyme of oxylipin biosynthesis in brown algae. |
| PMID: | 27863255 |
| Journal: | Nature |
| Year: | 2017/2/ |
| Title: | The Ectocarpus genome and the independent evolution of multicellularity in brown algae. |
| PMID: | 20520714 |
| Journal: | Biochimica et biophysica acta. Molecular and cell biology of lipids |
| Year: | 2010/6/3 |