Detail Information
P450 Protein:
| P450 Symbol | CYP736A121 |
| Protein Name | |
| Uniprot ID | |
| Species | Angelica pubescens |
| Txid | 312530 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C14H14O3 → C14H14O4 |
| Reaction Type | Cyclization |
| Chemical Bond |
CYP736A121
Substrate Information:
| Substrate Name | Osthenol |
| Substrate Chemical Formula | C14H14O3 |
| Substrate PubChem CID | 5320318 |
| Substrate CAS Number | 484-14-0 |
| Substrate Smiles | CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)O)C |
| Substrate Structure |
Product Information:
| Product Name | Columbianetin |
| Product Chemical Formula | C14H14O4 |
| Product PubChem CID | 92201 |
| Product CAS Number | 3804-70-4 |
| Product Smiles | CC(C)([C@@H]1CC2=C(O1)C=CC3=C2OC(=O)C=C3)O |
| Product Structure |
References:
| Title: | Enzymatic innovations in Angelica pubescens reveal dual coumarin biosynthetic pathways driving metabolic diversification |
| PMID: | 41612665 |
| Journal: | The Plant journal : for cell and molecular biology |
| Year: | 2026/1/29 |