Detail Information
P450 Protein:
| P450 Symbol | ApyO |
| Protein Name | RiPP biosynthesis cytochrome P450 ApyO |
| Uniprot ID | |
| Gene ID | 45117535 |
| Species | Burkholderia thailandensis E264 |
| Txid | 271848 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H39N5O10 → C30H37N5O10 |
| Reaction Type | Oxidation |
| Chemical Bond | C-C |
ApyO
Substrate Information:
| Substrate Name | / |
| Substrate Chemical Formula | C30H39N5O10 |
| Substrate Smiles | C(N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@H](C(O)=O)CC(O)=O |
| Substrate Structure |
Product Information:
| Product Name | / |
| Product Chemical Formula | C30H37N5O10 |
| Product Smiles | C(N)C(=O)N[C@H]1CC2=CC=C(O)C(C3C=C(C=CC=3O)C[C@@H](C(=O)N[C@H](C(O)=O)CC(O)=O)NC(=O)[C@H](CC(C)C)NC1=O)=C2 |
| Product Structure |
References:
| Title: | Biosynthesis of Macrocyclic Peptides with C-Terminal β-Amino-α-keto Acid Groups by Three Different Metalloenzymes |
| PMID: | 38799663 |
| Journal: | ACS Cent Sci |
| Year: | 2024/4/11 |